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Effects of acute exercise on angiotensin I‐converting enzyme (ACE) activity in horses
Author(s) -
DE MELLO COSTA M. F.,
ANDERSON G. A.,
DAVIES H. M.,
SLOCOMBE R. F.
Publication year - 2012
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.2011.00461.x
Subject(s) - angiotensin converting enzyme , medicine , venous blood , athletes , horse , physical therapy , endocrinology , cardiology , blood pressure , biology , paleontology
Summary Angiotensin I‐converting enzyme (ACE) level measurement in blood samples is an important tool in human medicine for the detection, treatment and control of diseases such as sarcoidosis and hypertension. Recently ACE has been advocated as being correlated to athletic aptitude in human athletes and a genetic polymorphism has been shown to be responsible for the enzymatic levels in the circulation. The objective of this research was to evaluate the effects of acute exercise in horses in order to increase the understanding of a possible correlation between ACE levels in plasma and performance in equine athletes. A standardised exercise test (SET) to fatigue was conducted on 8 horses and repeated venous blood collections carried out for ACE activity measurements before, during and after the SET. Our results show an increase in ACE activity up to fatigue and a return to baseline values at 30 min post exercise.