Premium
Changes in arterial, mixed venous and intraerythrocytic ion concentrations during prolonged exercise
Author(s) -
MEYER N. D.,
BAYLY W. M.,
SIDES R. H.,
WARDROP K. J.,
SLINKER B. K.
Publication year - 2010
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.2010.00189.x
Subject(s) - medicine , cardiology , venous blood
Summary Reasons for performing study: Prolonged equine exercise can cause hypochloraemic alkalosis and hypokalaemia secondary to the loss of hypertonic sweat. Movement of ions in and out of erythrocytes during exercise may help regulate acid‐base balance and changes in plasma ion concentrations. The extent to which this happens during prolonged equine exercise has not been reported. Objectives: To measure changes in blood gases and major plasma and intraerythrocytic (iRBC) ion concentrations of horses undergoing prolonged submaximal exercise. Methods: Six horses were trotted at ∼30% V̇O 2max on a treadmill for 105 min. Arterial ( a ) and mixed venous ( v ) blood samples were collected every 15 min, and pre‐ and post exercise. Blood gases and plasma (pl) concentrations of sodium, potassium, chloride and protein were measured and their iRBC concentrations calculated and compared (P<0.05). Results: P a CO 2 decreased in all horses. pl[Cl ‐ ] v decreased and [HCO 3 ‐ ] v increased. Due to the exhalation of CO 2 and chloride shifting, [HCO 3 ‐ ] a <[HCO 3 ‐ ] v, pl[Cl ‐ ] a >pl[Cl ‐ ] v and iRBC[Cl ‐ ] a iRBC[K + ] v . Conversely, iRBC[Na + ] a