Premium
CD3+ and BLA.36+ cells do not occur in the epidermis and adnexal epithelia of normal equine skin
Author(s) -
TRANCHINA M. M.,
SCOTT D. W.,
McDONOUGH S. P.
Publication year - 2010
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.2010.00126.x
Subject(s) - epidermis (zoology) , pathology , horse , cd3 , population , biology , skin biopsy , biopsy , medicine , anatomy , antigen , immunology , cd8 , paleontology , environmental health
Summary A small population of resident T lymphocytes is present in the healthy human and murine epidermis. However, resident epidermal lymphocytes have not been reported in normal skin of the horse. Skin biopsy specimens from the normal skin of 27 horses were examined histologically and immunohistochemically for the presence of lymphocytes, CD3+ cells and BLA.36+ cells in epidermis and adnexal epithelia. All examinations were negative. It appears that lymphocytes occur rarely, if at all, in the epidermis and adnexal epithelia of normal horse skin. Hence, the presence of lymphocytes in these structures should be considered abnormal.