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Trema micrantha toxicity in horses in Brazil
Author(s) -
BANDARRA P. M.,
PAVARINI S. P.,
RAYMUNDO D. L.,
CORRÊA A. M. R.,
PEDROSO P. M. O.,
DRIEMEIER D.
Publication year - 2010
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.2010.00035.x
Subject(s) - coma (optics) , medicine , mikania micrantha , hepatic encephalopathy , necrosis , pathology , toxic encephalopathy , cerebral edema , encephalopathy , biology , gastroenterology , cirrhosis , agronomy , physics , weed , optics
Summary After ingesting green leaves of T. micrantha , 2 horses showed apathy, locomotor deficit, blindness, recumbency, paddling, coma and death. The main gross findings were scattered haemorrhages, enhanced lobular pattern of the liver, and cerebral oedema. Histological changes included disseminated haemorrhages, massive hepatocellular necrosis, neuronal degeneration, Alzheimer type II astrocytes and cerebral perivascular oedema. Clinicopathological findings which were comparable with those observed in Trema micrantha poisoned ruminants, associated with epidemiological evidence suggested the diagnosis. Trema micrantha poisoning should be evaluated as a possible cause in the diagnosis of equine hepatopathy and occasional secondary encephalopathy.