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The effect of age and diet on the oral glucose tolerance test in ponies
Author(s) -
MURPHY D.,
REID S. W. J.,
LOVE S.
Publication year - 1997
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.1997.tb03160.x
Subject(s) - medicine , hay , basal (medicine) , endocrinology , plasma glucose , breed , horse , oral administration , alfalfa hay , group b , biology , zoology , chemistry , rumen , insulin , biochemistry , paleontology , fermentation
Summary To evaluate the effects of age and diet on the oral glucose tolerance test (OGTT) in healthy ponies, OGTTs were performed on 2 groups of British native breed ponies ( Group A : 7 foals [6–9 months], Group B : 7 mature individuals [6–13 years]) when maintained on either a high fibre pelleted ration only ( Groups A and B ) or a hay only diet ( Group B ). Plasma glucose response, following oral glucose administration, for Group A (basal plasma glucose concentration [Glu 0 ] 4.6 ± 0.4 mmol/1 (mean ± s.d.) increasing to 11.5 ± 1.3 mmol/1 at 90 min) was significantly different (P<0.05) from that observed for Group B (Glu 0 of 4.3 ± 0.2 mmol/1 increasing to 6.8 ± 1.3 mmol/1 at 90 min), when fed the same diet. For Group B ponies, the plasma glucose response, following oral glucose administration, was significantly different (P<0.05) when fed hay only (Glu 0 4.6 ± 0.4 mmol/1 increasing to 9.6 ± 2.1 mmol/l at 150 min) compared to when fed the high fibre pelleted ration. These results indicate that both age and diet have a significant effect on plasma glucose concentrations measured during an OGTT.