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Gastric secretion in foals: measurement by nasogastric intubation with constant infusion and aspiration
Author(s) -
Andrews F. M.,
Jenkins Christine C.,
Frazier Donita,
Blackford J. T.
Publication year - 1992
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.1992.tb04792.x
Subject(s) - phenol red , horse , medicine , gastric acid , suction , gastric secretion , liter , saline , stomach , chemistry , anesthesia , chromatography , biology , mechanical engineering , paleontology , engineering
Summary A technique comprising constant infusion and aspiration via nasogastric tube was used to quantify basal gastric secretion in 9 healthy foals aged 4–7 months and weighing 156 to 215 kg. Gastric fluid was collected continuously for 3 h from an in situ double lumen nasogastric tube attached to a constant suction device (5–10 mmHg). Phenol red (50 mg/litre), an inert marker, was infused continuously (250 ml/h) during the same period to determine loss of gastric fluid through the pylorus. Samples were collected every 15 mins and aspirated volume (V ASP ), pH, phenol red recovery (PRR) and hydrogen ion concentration (AO) were measured. Gastric secretory volume (V S ) and acid concentration (ACD) were calculated. The mean (sd) V ASP was 6.54 (1.31) ml/kg bodyweight (bwt)/h; pH was 1.76 (0.25), PRR was 77.7% (11.7), and AO was 0.43 (0.18) mmol/kg bwt/h. Mean (sd) ACD and V S were 59.17 (18.88) mmol/litre and 7.07 (1.73) ml/kg bwt/h, respectively. The AO, ACD, and V S were corrected for PRR. This technique is an alternative to invasive procedures and may be useful for evaluating basal and stimulated gastric secretion in foals and horses.