Premium
Arachidonate metabolites in bronchoalveolar lavage fluid from horses with and without COPD
Author(s) -
WATSON ELAINE D.,
SWEENEY C. R.,
STEENSMA K. A.
Publication year - 1992
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.1992.tb02859.x
Subject(s) - bronchoalveolar lavage , copd , horse , medicine , thromboxane , leukotriene , prostaglandin , pulmonary disease , prostaglandin d2 , immunology , lung , asthma , biology , platelet , paleontology
Summary Arachidonate metabolites were measured in bronchoalveolar lavage fluid (BALF) from horses with (N = 4) and without (N = 7) chronic obstructive pulmonary disease (COPD). Prostaglandin (PG) D 2 , leukotriene (LT) B 4 and LTC 4 were present in highest concentrations in BALF from clinically normal horses. Concentrations of PGE 2 and PGF were significantly higher in BALF from horses with COPD than in BALF from normal horses, but no differences were detected in thromboxane B 2 , 6‐keto‐PGF 1α , PGD 2 , LTB 4 or LTC 4 .