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Cardiovascular effects and fatalities associated with intravenous administration of doxycycline to horses and ponies
Author(s) -
RIOND J.L,
RIVIERE J. E.,
DUCKETT W. M.,
ATKINS C. E.,
JERNIGAN A. D.,
RIKIHISA Y.,
SPURLOCK S. L.
Publication year - 1992
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.1992.tb02777.x
Subject(s) - medicine , doxycycline , dose , anesthesia , tachycardia , supraventricular tachycardia , antibiotics , microbiology and biotechnology , biology
Summary Intravenous use of doxycycline in horses is associated with deleterious side effects on the cardiovascular system which may result in fatalities. At dosages and infusion rates used in these studies, supraventricular tachycardia, systemic arterial hypertension, clinical signs of discomfort, collapse and death were observed. Results of the present study suggest that the intravenous use of doxycycline should be avoided in horses.