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The effect of low dose heparin therapy on complication and survival rates in horses following exploratory celiotomy
Author(s) -
YOUNG D. R.,
RICHARDSON D. W.,
MARKEL M. D.
Publication year - 1989
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.1989.tb05664.x
Subject(s) - enterotomy , medicine , complication , placebo , heparin , saline , surgery , anastomosis , gastroenterology , anesthesia , laparotomy , alternative medicine , pathology
Summary A randomised, blind prospective study was performed to evaluate effects of low dose heparin therapy on complication and survival rates in 33 horses following exploratory celiotomy. Four horses had non‐strangulating lesions and seven had strangulating lesions of the small intestine, 19 had non‐strangulating lesions of the large intestine, and three had duodenitis‐proximal jejunitis. Eighteen required an enterotomy or intestinal resection and anastomosis. Sixteen received heparin subcutaneously (66 iu/kg every 12 h) post operatively and 17 received a saline placebo for a mean of 3.7 days. There was a significant (P<0.01) mean decrease in PCV (29.1 per cent) in the heparin group. No significant differences in complication or survival rates were seen between groups. Long term follow‐up was obtained for 10 horses in each group. There were no significant differences between groups.