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Ventilation imaging in the horse with 99m technetium‐DTPA radioaerosol
Author(s) -
O'CALLAGHAN M. W.,
HORNOF W. J.,
FISHER P. E.,
RABBE O. G.
Publication year - 1987
Publication title -
equine veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.82
H-Index - 87
eISSN - 2042-3306
pISSN - 0425-1644
DOI - 10.1111/j.2042-3306.1987.tb02570.x
Subject(s) - technetium 99m , nuclear medicine , horse , ventilation (architecture) , lung ventilation , medicine , lung , technetium , isotopes of technetium , technetium 99 , scintigraphy , physics , biology , paleontology , thermodynamics
Summary This study describes the development of a radioaerosol technique for horses using 99m technetium‐DTPA (diethylene‐triaminepentacetate). In 24 normal, adult horses, very satisfactory ventilation images were obtained with the technique. Four‐minute administrations of the aerosol resulted in a mean uptake of radioactivity in the lung fields of 3.02 mCi, with mean maximum counts (±sd) of 159,800± 75,000 per camera field. The mean clearance half‐time for the 99m technetium‐DTPA from the lung fields was 55.6 ± 14.2 mins which is very similar to figures obtained for normal human and dog lungs. The results of this study suggest that ventilation imaging with 99m technetium‐DTPA is a clinically practical method of obtaining regional information on ventilation function in the horse.