Open AccessFat Feeding Increases Equine Heparin‐Released Lipoprotein Lipase Activity
Author(s) -
Geelen Suzanne N.J.,
Jansen Walter L.,
OldruitenborghOosterbaan Marianne M. Sloet,
Breukink Henk J.,
Beynen Anton C.
Publication year - 2001
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/j.1939-1676.2001.tb01578.x
Subject(s) - lipoprotein lipase , hay , dry matter , endocrinology , latin square , medicine , cholesterol , heparin , soybean oil , fatty acid , food science , zoology , chemistry , biochemistry , biology , adipose tissue , rumen , fermentation
The aim of this study was to establish the dose‐response relationship between fat intake and heparin‐released plasma lipoprotein lipase (LPL) activity in horses. Eight mature trotters were fed 4 rations with different fat levels (3.0, 5.0, 7.7, or 10.8% fat in the dry matter) according to a 4 × 4 Latin square design. The experimental rations consisted of hay and different concentrates; the concentrates and hay were given in a 3 :1 ratio on an energy basis. Soybean oil was added to the concentrates at the expense of isoenergetic amounts of glucose. Blood samples were taken at the end of each dietary period, which lasted 3 weeks. Fat feeding was found to increase heparin‐released plasma LPL activity in a dose‐dependent fashion. When the data from this study and previous studies were combined it was calculated that an increase in fat intake by 1 g/kg dry matter is associated with an increase in LPL activity by 0.98 μmol fatty acid released.mL ‐1 .h ‐1 . Fat feeding raised the plasma concentrations of total cholesterol, high‐density lipoprotein cholesterol, and phospholipids. Diet did not have a statistically significant effect on plasma triacylglycerol concentrations. The results are discussed in the light of the possible enhancing effect of fat feeding on the oxidative capacity of skeletal muscle.