Open AccessPrediction of Serum IgG1 Concentration in Holstein Calves Using Serum Gamma Glutamyltransferase Activity
Author(s) -
Parish Steven M.,
Tyler Jeff W.,
Besser Thomas E.,
Gay Clive C.,
Krytenberg Denise
Publication year - 1997
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/j.1939-1676.1997.tb00478.x
Subject(s) - gamma glutamyltransferase , medicine , serum concentration , endocrinology , antibody , zoology , blood sampling , blood serum , immunology , biology , enzyme , biochemistry
We examined the relationship between serum gamma glutamyltransferase (GGT) activity and serum gamma immunoglobulin G (IgG1) concentration in Holstein calves. Blood samples were collected from calves aged 1 to 3 days. A follow‐up sample was obtained from each calf 2, 7, or 15 days after the initial sampling. Serum GGT activity and lgG1 concentration were measured. Regression models were used to predict lgG1 concentration as a function of age and serum GGT activity measured 2, 7, or 15 days later. Serum GGT activity and calf age at the time of the second sample were directly related to serum IgG1 concentration in the initial sample in calves aged 3 to 17 days ( r = .54) and in calves aged 3 to 10 days ( r = .63). Models were used to estimate the serum GGT activity equivalent to a serum IgG1 concentration of 1,000 mg/dL. One‐day‐old calves should have serum GGT activities > 200 IU/L. Four‐day‐old calves should have serum GGT activities > 100 IU/L. One‐week‐old calves should have serum GGT activities > 75 IU/L. Calves with serum GGT activities < 50 IU/L should be classified as having failure of passive transfer.