Open AccessPancytopenia Secondary to Lymphoid Leukemia in Three Horses
Author(s) -
Lester Guy D.,
Alleman Arthur R.,
Raskin Rose E.,
Meyer James C.
Publication year - 1993
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/j.1939-1676.1993.tb01031.x
Subject(s) - pancytopenia , medicine , bone marrow , horse , pathology , anorexia , spleen , lymph , paleontology , biology
Pancytopenia was observed in two 3‐year‐old geldings and one 11‐year‐old mare. All horses had a brief history (2 days to 4 weeks) of fever, anorexia, and depression. One of the three horses had blast cells present on a peripheral blood smear. Examination of the bone marrow showed substantial infiltration with neoplastic lymphoid cells. At necropsy, neoplastic cells were restricted to the bone marrow in one horse, present in bone marrow, liver, and spleen in the second horse, and reported in multiple tissues in the third horse, including bone marrow, kidneys, lung, myocardium and lymph nodes. The value of a bone marrow aspirate and core biopsy in the investigation of pancytopenia is highlighted. (Journal of Veterinary Internal Medicine 1993; 7:360–363. Copyright © 1993 by the American College of Veterinary Internal Medicine.)