Open AccessDyserythropoiesis, Polymyopathy, and Cardiac Disease in Three Related English Springer Spaniels
Author(s) -
Holland Christopher T.,
Canfield Paul J.,
Watson A. David J.,
Allan Graeme S.
Publication year - 1991
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/j.1939-1676.1991.tb00942.x
Subject(s) - medicine , megaesophagus , regurgitation (circulation) , etiology , atrophy , pathology , anemia , trismus , cardiology , disease , surgery , esophagus
A polysystemic disorder was observed in three related English Springer Spaniel dogs that demonstrated regurgitation from an early age, slowly progressive temporal muscle atrophy with partial trismus, and less pronounced generalized skeletal muscle atrophy. All dogs exhibited moderate dyserythropoietic anemia, polymyopathy with megaesophagus, and varying degrees of cardiomegaly. The prevalence, etiology, underlying pathomechanism, and possible mode of inheritance remain to be elucidated.