Open AccessPropionibacterium acnes Immunotherapy in Chronic Recurrent Canine Pyoderma
Author(s) -
Becker A. M.,
Janik A.,
Smith E. K.,
Sousa C. A.,
Peters B. A.
Publication year - 1989
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/j.1939-1676.1989.tb00325.x
Subject(s) - medicine , propionibacterium acnes , pyoderma , antibiotics , placebo , dermatology , surgery , gastroenterology , pathology , acne , microbiology and biotechnology , alternative medicine , biology
In a randomized, double‐blind, placebo‐controlled study, dogs with chronic recurrent pyoderma were treated with antibiotics plus intravenous injections of either Propionibacterium acnes or placebo. Responses (an increase, decrease, or clearing of lesions) were measured and evaluated statistically. Eighty percent (12 of 15) of the dogs treated with antibiotics and P acnes compared with 38% (five of 13) of the dogs treated with antibiotics and placebo responded with significant improvement or complete remission of lesions at the end of the 12‐week treatment schedule (P < 0.05).