Open AccessFine‐Needle Aspiration of the Spleen as an Aid in the Diagnosis of Splenomegaly
Author(s) -
O'Keefe Deborah A.,
Couto C. Guillermo
Publication year - 1987
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/j.1939-1676.1987.tb01997.x
Subject(s) - medicine , extramedullary hematopoiesis , pathology , spleen , hemangiosarcoma , bone marrow , fine needle aspiration , systemic mastocytosis , plasmacytoma , anemia , hypoplasia , hyperplasia , leukemia , haematopoiesis , multiple myeloma , biopsy , angiosarcoma , stem cell , genetics , biology
Results from transabdominal fine‐needle aspiration of the spleen in 28 dogs and 5 cats are reported. Splenomegaly was present in 79% of these patients, and splenic masses were present in 15%. Extramedullar hematopoiesis, the most common cytologic diagnosis, was found in 24% of the patients and was associated with a variety of diseases including immune hemolytic anemia, hemangiosarcoma, and bone marrow hypoplasia. Hematopoietic neoplasms including lymphosarcoma, plasmacytoma, myelogenous leukemia, and systemic mastocytosis were diagnosed in 24% of the patients. Other diagnoses included malignant neoplasia of undetermined cell type and lymphoreticular hyperplasia. Splenic aspirates were considered normal in 18% of the animals. Two (6%) of the aspirates contained liver tissue rather than spleen. Histologic evaluation of splenic tissue was performed in 42.5% of the patients. All cytologic diagnoses correlated well with their final histologic diagnoses. Complications from the aspiration procedure were not observed, even in thrombocytopenic patients.