Open AccessInsulinoma and Subclinical Peripheral Neuropathy in Two Dogs
Author(s) -
Braund Kyle G.,
Steiss Janet E.,
Amling Karen A.,
ToivioKinnucan Maria,
Case Lisa C.,
Kemppainen Robert J.,
Coleman Elaine S.
Publication year - 1987
Publication title -
journal of veterinary internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.356
H-Index - 103
eISSN - 1939-1676
pISSN - 0891-6640
DOI - 10.1111/j.1939-1676.1987.tb01992.x
Subject(s) - medicine , subclinical infection , polyneuropathy , remyelination , axonal degeneration , peripheral , peripheral neuropathy , pathology , peripheral nervous system , paralysis , cranial nerves , myelin , anatomy , central nervous system , surgery , diabetes mellitus , endocrinology
Two dogs with diffuse, subclinical polyneuropathy associated with insulinoma are reported. Seizures were the dominant sign of central nervous system disease. One dog had clinical signs of facial nerve paralysis. Lesions in selected appendicular and cranial nerves included a mixture of demyelination, remyelination, and axonal degeneration. The incidence (range: 18–47%) of these changes far exceeded that of comparable nerves from six control dogs (range 0–11%). Myopathic and electrodiagnostic findings were compatible with the nerve changes.