Premium
Characterization of Portal Lymphocytic Infiltrates in Feline Liver
Author(s) -
Weiss Douglas J.,
Gagne J. M.,
Armstrong P. Jane
Publication year - 1995
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/j.1939-165x.1995.tb00946.x
Subject(s) - medicine , cats , pathology , portal hypertension , liver disease , fibrosis , gastroenterology , cirrhosis
To better understand the relationship of portal lymphocytic infiltrates to feline inflammatory liver disease, liver sections were semiquantitatively evaluated from healthy cat and liver sections randomly selected at necropsy from clinical cases. Healthy specific pathogen‐free kittens and healthy young adult cats had up to 10 lymphocytes and plasma cells per portal area. Neutrophils were infrequently seen in portal areas. Approximately one‐third of sections obtained from clinical cases younger than 10 years had increased numbers of lymphocytes and plasma cells in portal areas. Seventy percent of these had a concurrent increase in neutrophils. Eighty‐two percent of liver sections obtained from clinical cases older than 10 years had increased numbers of portal lymphocytes and plasma cells. Almost all of these sections had concurrent fibrosis and bile duct proliferation. These data indicate that a progressive lymphocytic portal hepatitis is a common finding in cats older than 10 years.