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Effects of Cadmium on Erythrocytic Parameters
Author(s) -
Waner Trevor,
Gur Ephraim
Publication year - 1993
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/j.1939-165x.1993.tb00872.x
Subject(s) - cadmium , anemia , hemoglobin , adverse effect , microcytic anemia , medicine , hypochromic anemia , chemistry , physiology , organic chemistry
Cadmium was administered via the drinking water to rats at doses of 20 and 200 ppm for 5 weeks in order to elucidate cadmium's primary effect on the erythrocytic parameters. From the results, it appeared that the microcytic hypochromic anemia resulted from a direct effect on erythrocytic hemoglobin due to cadmium administration. It was proposed that the adverse effects on hemoglobin absorption and metabolism play a role in the development of the anemia observed.