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Mediastinal Schwannoma in a Horse ‐ Cytologic, Histologic, and Immunochemical Evaluation
Author(s) -
Andreasen Claire B.,
Hedstrom Olaf R.,
Allison Patricia
Publication year - 1993
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/j.1939-165x.1993.tb00606.x
Subject(s) - vimentin , pathology , schwannoma , cytokeratin , desmin , cytology , cytoplasm , horse , anatomy , biology , immunohistochemistry , medicine , microbiology and biotechnology , paleontology
A 31‐kg mediastinal mass from a 24‐year‐old horse is described. Cytologic imprints contained numerous spindle cells with indistinct cytoplasm and multiple foci of palisading nuclei. Histologic sections had these same characteristics and areas of central fibrillar material between palisading nuclei (Verocay bodies). Within histologic sections, spindle cell cytoplasm had positive immunoreactivity for vimentin and S‐100, whereas immunoreactivity was not detected for desmin and cytokeratin. Cytologic, histologic, and immunochemical evaluation confirmed a diagnosis of solitary schwannoma.