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Serum Procollagen Type III Peptide Levels in Normal Rhesus Monkeys
Author(s) -
Cornelius Charles,
Strong Sharon,
Smith Carrie,
Lee Blaine
Publication year - 1990
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/j.1939-165x.1990.tb00554.x
Subject(s) - radioimmunoassay , endocrinology , medicine , procollagen peptidase , peptide , age groups , biology , chemistry , biochemistry , demography , sociology
Summary Serum levels of the amino‐terminal peptide of Type III procollagen (P‐III‐P) were assayed by radioimmunoassay in 48 Rhesus monkeys from 0.7 to 26.4 years of age. Serum P‐III‐P levels in ten juvenile monkeys (0.7‐4.7 yrs.) were significantly higher (84.5 ± 66.2 ng/ml; p = 0.05) and ranged from 29.6 to 238.0 ng/ml as compared with 38 monkeys over 5 years of age (21.7 ± 9.4 ng/ml), which ranged from 8.5 to 55.5 ng/ml. No significant differences in serum P‐III‐P levels were observed between any age groups over 5 years of age (5–10, 10–15, 15–20, and > 20) or between male and female monkeys within any age category.