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Lipoprotein Electrophoresis Differentiation of Chylous and Nonchylous Pleural Effusions in Dogs and Cats and Its Correlation with Pleural Effusion Triglyceride Concentration
Author(s) -
Waddle Jerry R.,
Giger Urs
Publication year - 1990
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/j.1939-165x.1990.tb00548.x
Subject(s) - cats , chylomicron , triglyceride , medicine , chylous ascites , cholesterol , pleural effusion , gastroenterology , effusion , lipoprotein , pathology , very low density lipoprotein , surgery , ascites
Summary Pleural effusions from 23 dogs and 25 cats hospitalized between November 1986 and April 1987 at the Veterinary Hospital of the University of Pennsylvania (VHUP) were classified as chylous (chylomicrons present) or nonchylous (chylomicrons absent) by the presence or absence, respectively, of a chylomicron band on lipoprotein electrophoresis gels of the effusions. Triglyceride concentrations, cholesterol concentrations, and cholesterol/triglyceride (C/T) ratios were compared between the chylous and nonchylous groups in each species. Cholesterol concentrations were not significantly different between chylous and nonchylous effusions in both dogs and cats. Cholesterol/triglyceride ratios of less than 1 were present in all dogs and cats with chylous effusions; however, 12% of dogs with nonchylous effusions and 50% of cats with nonchylous effusions also had a C/T ratio less than 1. Triglyceride concentrations accurately classified all effusions as chylous or nonchylous in both dogs and cats. Pleural effusions with triglyceride concentrations greater than 100 mg/dl were chylous in all cases, whereas, effusions with triglyceride concentrations less than 100 mg/dl were nonchylous in all cases.