Premium
Hepatic Bilirubin‐IX‐ α ‐Glycosyltransferase Activities in Animals Excreting Primarily Biliverdin into Bile
Author(s) -
Cornelius Charles E.
Publication year - 1981
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/j.1939-165x.1981.tb00801.x
Subject(s) - biliverdin , bilirubin , enzyme , glycosyltransferase , biology , biliverdin reductase , biochemistry , glucuronosyltransferase , medicine , transferase , endocrinology , heme , heme oxygenase , microsome
Summary A wide variation was observed in hepatic bilirubin‐IX‐α undine diphosphate (UDP) glu‐curonyl, glucosyl and xylosyl transferase activities among yellow rat snakes, pin fish, chickens, turkeys, sea turtles, alligators, nutria and rats. Lower hepatic enzyme activities were observed in fish, snakes, turtles, and avian species with intermediate enzyme activities present in the livers of nutria and alligators. Hepatic glycosyltransferase activities were greater in the biliverdin‐excreting species which are known to excrete readily an exogenous bilirubin load. Hepatic enzyme activities and the biliary transport maxima of bilirubin‐IX‐α are closely correlated.