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The Anemia of Chronic Renal Failure Revisited
Author(s) -
Easley J. Roger
Publication year - 1981
Publication title -
veterinary clinical pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 51
eISSN - 1939-165X
pISSN - 0275-6382
DOI - 10.1111/j.1939-165x.1981.tb00797.x
Subject(s) - erythropoietin , anemia , chronic renal failure , erythropoiesis , medicine , secretion , parathyroid hormone , pure red cell aplasia , ineffective erythropoiesis , endocrinology , calcium
Summary The mechanisms of the anemia of chronic renal failure are reviewed. Ineffective erythro‐poiesis is undoubtedly the major cause of this anemia. The contributions of inadequate erythropoietin secretion by the diseased kidneys, suppressive effects of uremic “toxins” on erythropoiesis and red cell survival, excess blood loss, and plasma concentrations of parathyroid hormone, calcium and phosphate are discussed.