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Treatment algorithm for hepatocellular carcinoma
Author(s) -
Michel Ducreux,
Paul Brousse
Publication year - 2010
Publication title -
hepatology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.123
H-Index - 75
eISSN - 1872-034X
pISSN - 1386-6346
DOI - 10.1111/j.1872-034x.2010.00653.x
Subject(s) - hepatocellular carcinoma , medicine , liver damage , carcinoma , liver cancer , hepatology , hepatectomy , algorithm , gastroenterology , oncology , surgery , computer science , resection
SCIENTIFIC STATEMENT We specified a treatment algorithm for hepatocellular carcinoma based on three factors: degree of liver damage, number of tumors and tumor diameter. For patients with the severity of the liver damage categorized into class A or B, first, hepatectomy is recommended, regardless of tumor diameter, if a single tumor is present. However, local ablation therapy can also be selected if the severity of liver damage is class B and the tumor diameter is 2 cm or less (LF00178 level 2b). Second, hepatectomy or local ablation therapy is recommended when the number of tumors is two or three and their diameter is 3 cm or less (LF00178 level 2b). Third, hepatectomy or transcatheter arterial embolization (TAE) is recommended when the number of tumors is two or three and their diameter is larger than 3 cm (LF06283 level 1b). Fourth, TAE or hepatic arterial infusion chemotherapy is recommended when the number