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An autopsy case of obstructive jaundice due to hepatic multiple peribiliary cysts accompanying hepatolithiasis
Author(s) -
Kai Keita,
Eguchi Yuichiro,
Kumagai Takafumi,
Sugita Yasuo,
Tokunaga Osamu
Publication year - 2008
Publication title -
hepatology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.123
H-Index - 75
eISSN - 1872-034X
pISSN - 1386-6346
DOI - 10.1111/j.1872-034x.2007.00211.x
Subject(s) - hepatolithiasis , medicine , autopsy , jaundice , intrahepatic bile ducts , obstructive jaundice , cirrhosis , cholestasis , gastroenterology , biliary cirrhosis , hepatocellular carcinoma , cholangiography , bile duct , common bile duct , common hepatic duct , surgery , hepatectomy , resection , disease , autoimmune disease
A 73‐year‐old Japanese male, who had a history of alcoholic cirrhosis, was admitted to Saga University Hospital to receive treatment for hepatocellular carcinoma. The patient was treated to maintain his liver function, however, the total bilirubin level continued to increase gradually. Endoscopic retrograde cholangiography demonstrated an obstruction of the bilateral intrahepatic ducts. Although endoscopic nasobiliary drainage was performed, the patient died two months after admission. At the autopsy, multiple peribiliary cysts were found to almost completely obstruct the bilateral intrahepatic bile ducts. In addition, hepatolithiasis was found in the right hepatic duct. To date, only a few such cases of multipleperibiliary cysts with obstructive jaundice have been reported, and no such case accompanied by hepatolithiasis. It is also important to note that all the reported cases resulted in a poor prognosis. We herein report a very rare autopsy case with obstructive jaundice due to multiple peribiliary cysts accompanying hepatolithiasis. Generally, multiple peribiliary cysts are considered to be clinically harmless, but once they cause obstructive jaundice, their presence suggests the occurrence of end‐stage cirrhosis and a poor prognosis.