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Review of current staging systems for hepatocellular carcinoma
Author(s) -
Chung Hobyung,
Kudo Masatoshi,
Takahashi Shunsuke,
Hagiwara Satoru,
Sakaguchi Yasuhiro,
Inoue Tatsuo,
Minami Yasunori,
Ueshima Kazuomi,
Fukunaga Toyokazu
Publication year - 2007
Publication title -
hepatology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.123
H-Index - 75
eISSN - 1872-034X
pISSN - 1386-6346
DOI - 10.1111/j.1872-034x.2007.00187.x
Subject(s) - hepatocellular carcinoma , staging system , medicine , stage (stratigraphy) , liver cancer , tumor stage , tnm staging system , oncology , tumor staging , radiology , cancer , paleontology , biology
Several staging systems have been developed to classify patients with hepatocellular carcinoma (HCC), however, there is no consensus on which of these is the most useful and reliable. In this review article, currently available integrated staging systems taking into account both liver function and tumor progression are presented, and their characteristics and applicability for current HCC patients, many of whom are diagnosed in the early stage of the disease and treated by curative therapy, are discussed. Based on the original andsubsequent validation studies of these staging systems, we recommend that further validation studies of staging systems for HCC should focus on the revised Barcelona Clinic Liver Cancer (BCLC) staging classification, Japan Integrated Staging (JIS) score and Tokyo score.