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Novel approaches to assessing renal function in cirrhotic liver disease
Author(s) -
Portal Andrew J.,
Austin Mark,
Heneghan Michael A.
Publication year - 2007
Publication title -
hepatology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.123
H-Index - 75
eISSN - 1872-034X
pISSN - 1386-6346
DOI - 10.1111/j.1872-034x.2007.00086.x
Subject(s) - hepatorenal syndrome , renal function , medicine , creatinine , liver disease , acute tubular necrosis , nephropathy , disease , gastroenterology , etiology , liver function tests , pathology , cirrhosis , endocrinology , diabetes mellitus
Renal dysfunction is common in patients with end‐stage liver disease. Etiological factors include conditions as diverse as acute tubular necrosis, immunoglobulin A nephropathy and hepatorenal syndrome. Current standard tests of renal function, such as measurement of serum urea and creatinine levels, are inaccurate as the synthesis of these markers is affected by the native liver pathology. This article reviews novel markers of renal function and their potential use in patients with liver disease.