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Hepatitis C virus infection among HIV‐1 infected individuals from northern Mexico
Author(s) -
RivasEstilla Ana M.,
RamírezValles Eda,
MartinezHernández Ramón,
CharlesNiño Claudia,
RamírezCamacho Ericka,
RositasNoriega Felix,
GarzaRodriguez Maria L.,
BarreraSaldaña Hugo A.,
TrujilloMurillo Karina,
RamosJimenez Javier
Publication year - 2007
Publication title -
hepatology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.123
H-Index - 75
eISSN - 1872-034X
pISSN - 1386-6346
DOI - 10.1111/j.1872-034x.2007.00035.x
Subject(s) - coinfection , hepatitis c virus , genotype , medicine , sexual transmission , hepatitis c , virology , genotyping , transmission (telecommunications) , men who have sex with men , flaviviridae , immunology , human immunodeficiency virus (hiv) , virus , biology , syphilis , biochemistry , microbicide , electrical engineering , gene , engineering
Aims: The prevalence of hepatitis C virus (HCV) infection, risk factors and HCV genotypes in 140 HIV‐1 infected individuals from northern Mexico was determined. Methods: Hepatitis C infection was confirmed by the detection of anti‐HCV antibodies and HCV‐RNA in sera, and genotyping was performed by the InnoLiPA‐HCV genotype assay. Results: Seventeen (12.1%) out of 140 HIV‐infected individuals were found to be HCV‐positive. Coinfected individuals were more likely to be male (87%). The most frequent genotype was 1a (41%), followed by 1b (29.4%), 2a/c (17.6%), 2b (5.9%) and 3 (5.9%). Serum transaminase concentrations (AST and ALT) were higher in coinfected patients. Among the risk factors for coinfection: sexual transmission was the most frequently observed (men who have sex with men (MSM); 64.7% and bisexual behavior; 64.7%) followed by intravenous drug users (IVDU) (53%). There was no association of the HCV genotypes with the age and risk factors for HIV‐1 and HCV infection observed in the studied patients. Conclusion: The results suggest that the prevalence of HIV‐1/HCV coinfection in Mexico is lower than in other American countries.