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Spontaneous Cutaneous Papillomatosis in Yaks and Detection and Quantification of Bovine Papillomavirus‐1 and ‐2
Author(s) -
Bam J.,
Kumar P.,
Leishangthem G. D.,
Saikia A.,
Somvanshi R.
Publication year - 2013
Publication title -
transboundary and emerging diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.392
H-Index - 63
eISSN - 1865-1682
pISSN - 1865-1674
DOI - 10.1111/j.1865-1682.2012.01361.x
Subject(s) - bovine papillomavirus , papillomatosis , biology , sybr green i , virology , polymerase chain reaction , real time polymerase chain reaction , pathology , medicine , gene , genome , genetics
Summary Seven clinical cases of cutaneous papillomatosis in yaks were studied in Arunachal Pradesh, India. Sporadic, single or a chain of multiple varying size warts appeared around the eyes or on the body. Predominant site of warts was around eyes. Histopathologically, these cases were diagnosed as fibropapilloma. It was confirmed by the detection of BPV‐1 and BPV‐2 or their mixed infection by PCR and sequencing. Quantitative SYBR Green real‐time PCR detected comparatively lower viral DNA copy number in cutaneous warts (CWs). Cases of CWs and its causative agent as bovine papillomavirus (BPVs) are reported for the first time in yaks.