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Genomic Tandem Repeat Analysis Proves Laboratory‐Acquired Brucellosis in Veterinary (Camel) Diagnostic Laboratory in the United Arab Emirates
Author(s) -
Zur Wiesch J. Schulze,
Wichmann D.,
Sobottka I.,
Rohde H.,
Schmoock G.,
Wernery R.,
Schmiedel S.,
Dieter Burchard G.,
Melzer F.
Publication year - 2010
Publication title -
zoonoses and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.87
H-Index - 65
eISSN - 1863-2378
pISSN - 1863-1959
DOI - 10.1111/j.1863-2378.2009.01258.x
Subject(s) - brucellosis , brucella , brucella melitensis , veterinary medicine , multiple loci vntr analysis , medicine , tandem repeat , biology , biochemistry , gene , genome
Summary We report a case of a 64‐year‐old veterinarian working in a state camel veterinary laboratory who was diagnosed with and treated for acute brucellosis with complicating epididymo‐orchitis. Genomic tandem repeat analysis (MLVA‐16) revealed identical Brucella strains in patient cultures and from different dromedary milk samples positive for Brucella melitensis , thereby confirming the diagnosis of a laboratory acquired infection. The case illustrates the high (airborne) infectivity of brucellosis in laboratory settings and the need to implement vigorous bio‐safety measures in veterinary laboratories handling camel specimen diagnostic veterinary laboratory.