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Characterization of Virulence Properties of Listeria monocytogenes Serotype 4b Strains of Different Origins
Author(s) -
Werbrouck H.,
Botteldoorn N.,
Ceelen L.,
Decostere A.,
Uyttendaele M.,
Herman L.,
Van Coillie E.
Publication year - 2008
Publication title -
zoonoses and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.87
H-Index - 65
eISSN - 1863-2378
pISSN - 1863-1959
DOI - 10.1111/j.1863-2378.2008.01127.x
Subject(s) - virulence , listeria monocytogenes , serotype , biology , microbiology and biotechnology , listeria , bacteria , genetics , gene
Summary In this study, the virulence heterogeneity of Listeria monocytogenes serotype 4b strains of different origins was analysed on different levels. On one hand, the survival of L. monocytogenes strains in synthetic gastric fluid was studied. On the other hand, the pathogenic potential of strains with different inlB expression levels was analysed in an A/J mouse model for gastrointestinal listeriosis. Differences in survival capacity in gastric fluid and in in vivo virulence potential were observed between the tested strains. No clear correlation between the origin and the obtained data could be made. However, these results confirm the existence of heterogeneity in virulence potential of L. monocytogenes serotype 4b strains.