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The dentine remineralization activity of a desensitizing bioactive glass‐containing toothpaste: an in vitro study
Author(s) -
Wang Z,
Jiang T,
Sauro S,
Pashley DH,
Toledano M,
Osorio R,
Liang S,
Xing W,
Sa Y,
Wang Y
Publication year - 2011
Publication title -
australian dental journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 71
eISSN - 1834-7819
pISSN - 0045-0421
DOI - 10.1111/j.1834-7819.2011.01361.x
Subject(s) - toothpaste , remineralisation , dentinal tubule , dentine hypersensitivity , bioactive glass , demineralization , dentin hypersensitivity , dentistry , chemistry , fourier transform infrared spectroscopy , citric acid , dentin , glass ionomer cement , nuclear chemistry , materials science , enamel paint , food science , chemical engineering , medicine , engineering
Background: Dentine hypersensitivity occurs easily on exposed dentine. This study aimed to evaluate the effectiveness of a novel bioactive glass‐containing toothpaste on dentine permeability and remineralization. Methods: Thirty dentine discs were divided into three groups of 10 specimens each. The groups corresponded to the following brushing treatments: no brush, distilled water, and bioactive glass‐containing toothpaste (Novamin). The toothpaste was applied twice a day for 7 days. Dentine permeability was measured after ethylene‐diamine‐tetraacetic acid (EDTA) etching, initial application, 3‐day application, 7‐day application and citric acid challenge, respectively. The dentine morphology was investigated using scanning electron microscopy (SEM). Attenuated total reflection Fourier transform infrared (ATR/FTIR) spectroscopy was performed to monitor the mineral variation on demineralized dentine. Qualitative information of elemental variation before and after treatments on completely demineralized dentine was detected by energy dispersive X‐ray (EDX) analysis. Results: The bioactive glass‐containing toothpaste significantly reduced dentine permeability after the 7‐day treatment and showed, under SEM, excellent resistance to acid challenge compared to the other groups. ATR/FTIR and EDX revealed increased mineral content after treatment with Novamin. Conclusions: As the innovative bioactive glass‐containing toothpaste occlude dentinal tubules and resist acid challenge, it may be useful for the treatment of dentine hypersensitivity and dentine remineralization.