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Reaction of rat pulp tissue to Carisolv ‘new gel’—‐A histocytological evaluation
Author(s) -
Dammaschke T.,
Stratmann U.,
Danesh G.,
Schäfer E.,
Ott KHR
Publication year - 2006
Publication title -
australian dental journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 71
eISSN - 1834-7819
pISSN - 0045-0421
DOI - 10.1111/j.1834-7819.2006.tb00402.x
Subject(s) - pulp (tooth) , pulp capping , dentistry , molar , calcium hydroxide , chemistry , saline , medicine , anesthesia
Background : This study was an histological examination of pulp tissue exposed to Carisolv ‘new gel’ after 1 to 28 days. Methods : An occlusal cavity was prepared in 64 caries‐free molar teeth of 16 Wistar rats. The roofsof the pulp chambers were perforated and Carisolv ‘new gel’ solution was placed onto the exposed pulps of 32 molar teeth for 20 minutes. Thirty‐two contralateral molar teeth served as controls and were coated with an inert liquid containing isotonic saline solution and carmellose for 20 minutes as well. The pulps of all teeth were capped with Ca(OH) 2 and the cavities were filled with a flowable composite in combination with a self‐etching dentine adhesive. The animals were sacrificed after 1, 3, 7 and 28 days. Eight teeth per group and the time period were histologically examined, scored, and statistically evaluated (Wilcoxon‐test). Results : The results showed no statistically significant differences between the Carisolv group and the control group (p>0.05). The observed pulp reaction was essentially the same as those reported in the past being typical for the effect of calcium hydroxide as a direct pulp capping agent. Conclusion : Compared to Ca(OH) 2 , Carisolv ‘new gel’ did not cause any different or additional pulp reaction in healthy teeth.