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A concise review of the basic biology and pharmacology of local analgesia
Author(s) -
Subramaniam S.,
Tennant M.
Publication year - 2005
Publication title -
australian dental journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 71
eISSN - 1834-7819
pISSN - 0045-0421
DOI - 10.1111/j.1834-7819.2005.tb00380.x
Subject(s) - clinical pharmacology , neglect , safer , medicine , action (physics) , pharmacology , psychiatry , computer science , physics , computer security , quantum mechanics
Local analgesics are the most commonly used group drugs in dental practice. However, due to their frequent use and high margin of safety, often dental practitioners neglect to properly understand the biology and pharmacology of these drugs. This article reviews the basic concepts of pain, pain pathways, the mode of action of local analgesics and factors which affect their usage. Specific details and properties of some currently available solutions are also outlined. A greater understanding of the biology and pharmacology of local anaesthetics will ultimately lead to safer and more effective use in everyday clinical practice.