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Physiopathology of primary periodontitis associated with plaque. Microbial and host factors. A review. Part 1
Author(s) -
Liébana J.,
Castillo A.
Publication year - 1994
Publication title -
australian dental journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 71
eISSN - 1834-7819
pISSN - 0045-0421
DOI - 10.1111/j.1834-7819.1994.tb04782.x
Subject(s) - periodontitis , host (biology) , pathophysiology , primary (astronomy) , dental plaque , host factors , medicine , dentistry , microbiology and biotechnology , biology , pathology , immunology , ecology , virus , physics , astronomy
Microbial factors involved in the genesis of periodontitis include colonization, bacterial penetration of the epithelium, multiplication and invasive‐destructive capacity. Colonization of the gingival sulcus is related, to a certain extent, to supragingival plaque. Bacterial multiplication is induced by nutrients in the gingival fluid, and nutrients produced by degradative and excretory microbial activity. Invasion and destruction are mediated by exotoxins, structural elements of the bacteria, enzymes, metabolites, polyclonal lymphocyte activity, fibroblastic cytotoxicity, and leukocyte chemotactic inhibition.