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A clinical evaluation of three topical anaesthetic agents
Author(s) -
Vickers E. R.,
PunniaMoorthy A.
Publication year - 1992
Publication title -
australian dental journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 71
eISSN - 1834-7819
pISSN - 0045-0421
DOI - 10.1111/j.1834-7819.1992.tb04742.x
Subject(s) - medicine , benzocaine , placebo , anesthesia , lidocaine , prilocaine , visual analogue scale , topical anesthetic , surgery , alternative medicine , pathology
This study compared the efficacy of EMLA 5% Cream, Xylocaine 5% (lignocaine 5 per cent) and NUM (benzocaine 15 per cent, amethocaine 1.7 per cent) to a placebo in reducing the pain experience during needle insertion. In a random, double blind study three groups of twenty volunteers each had a paired topical anaesthetic/placebo placed bilaterally in the buccal sulcus of the upper premolar regions for two minutes, followed by the insertion of a standard 27 gauge needle to a depth of 5 mm. Pain experience was measured with visual analogue scales. Results showed that all three agents significantly reduced pain when compared with the placebo — EMLA ( p <0.002); Xylocaine ( p <0.05); NUM ( p <0.005).