Open AccessHyperchloremic Acidosis: Pathophysiology and Clinical Impact
Author(s) -
Burdett Edward,
Roche Antony M.,
Mythen Michael G.
Publication year - 2003
Publication title -
transfusion alternatives in transfusion medicine
Language(s) - English
Resource type - Journals
eISSN - 1778-428X
pISSN - 1295-9022
DOI - 10.1111/j.1778-428x.2003.tb00184.x
Subject(s) - medicine , acidosis , pathophysiology , intensive care medicine , anesthesia
SUMMARY Hyperchloremic acidosis is a predictable consequence of normal saline‐based fluid administration. The theoretical basis for this is easily understood using Stewart's model of acid‐base homeostasis. Data are emerging which describe the consequences of hyperchloremic acidosis in the surgical population.