Premium
Life cycles of yeast spindle pole bodies: Getting microtubules into a closed nucleus
Author(s) -
McIntosh J Richard,
O'Toole Eileen T
Publication year - 1999
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1111/j.1768-322x.1999.tb01089.x
Subject(s) - biology , spindle pole body , microtubule organizing center , microtubule , nucleus , budding yeast , astral microtubules , microbiology and biotechnology , yeast , spindle apparatus , cell cycle , cell division , cell , saccharomyces cerevisiae , genetics , centrosome
The spindle pole body (SPB) is the principal microtubule organizing center of budding and fission yeast. We have examined SPBs and their associated microtubules from both organisms, using electron microscopy and three‐dimensional reconstruction techniques, to identify the structural changes that accompany progression through the cell cycle. In this report, we compare these changes in the two kinds of yeasts and present a model for how microtubules get into a closed nucleus.