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Human autoimmune serum antibodies against gag gene p30 retroviral protein also react with a U1‐SnRNP 68K comigrant protein
Author(s) -
Rucheton M.,
Graafland H.,
Valles H.,
Larsen C. J.
Publication year - 1987
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1111/j.1768-322x.1987.tb00548.x
Subject(s) - snrnp , biology , group specific antigen , retrovirus , antibody , microbiology and biotechnology , epitope , rna , gene , virology , homology (biology) , ribonucleoprotein , immunology , biochemistry
Using Immunoblotting procedure, we showed that autoimmune human antibodies reacting with mouse retrovirus gag‐p30 also reacted with a HnRNP 68 Kd protein. Since U1‐SnRNP 68 K and p30‐gag proteins show 40% homology, the detected 68 Kd protein is likely to be the U1‐RNA 68 K.