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Monoclonal antibodies binding to nuclear structures and axons in adult avian dorsal root ganglia
Author(s) -
Masurovsky E. B.,
Fields K. L.
Publication year - 1984
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1111/j.1768-322x.1984.tb00318.x
Subject(s) - biology , monoclonal antibody , epitope , ultrastructure , cytoplasm , microbiology and biotechnology , nucleus , dorsum , anatomy , embryonic stem cell , antibody , immunology , genetics , gene
Four monoclonal antibodies raised against embryonic chick dorsal root ganglia (5) recognize epitopes in neuronal and supporting cell nuclei, and in axons and contiguous cytoplasmic elements in some neurons of the adult chicken. Binding, analyzed at the ultrastructural level, is to reaction sites on the nuclear matrix, nucleolar complex, nuclear bodies, and filamentous elements in axons and some perikaryal regions.