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TSH stimulation of iodine organification in early foetal rat thyroid in vitro
Author(s) -
Pic P.,
MichelBechet M.,
Bottini J.
Publication year - 1984
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1111/j.1768-322x.1984.tb00288.x
Subject(s) - organification , thyroid , stimulation , biology , iodine , medicine , follicular phase , endocrinology , follicular cell , in vitro , andrology , chemistry , biochemistry , organic chemistry
Thyroid glands from 15 day‐old rat foetuses were incubated in Eagle's medium containing Na 125I and supplemented, or not, with TSH for 4 or 24 hours. Electron microscopic radioautographic study shows silver grains mainly in follicular cavities only in the thyroids submitted to TSH during 24 hr. A functional differentiation must therefore take place in thyroid cells under TSH stimulation.