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Role of the thyroid in the involution of the mesonephric Malpighian corpuscles in the chick embryo
Author(s) -
Vergnaud O.,
Maraud R.
Publication year - 1984
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1111/j.1768-322x.1984.tb00287.x
Subject(s) - mesonephros , mesonephric duct , biology , embryo , thyroid , medicine , involution (esoterism) , endocrinology , hypophysectomy , embryonic stem cell , anatomy , microbiology and biotechnology , kidney , hormone , genetics , neuroscience , consciousness , gene
The mesonephros of the chick embryo normally begins to regress during the second half of embryonic life. Experimental methods, such as adenohypophysis grafting, hypophysectomy or use of antithyroid drugs, which stimulate or depress the thyroid function of the embryo, modified accordingly the regressive processes occurring in the mesonephric Malpighian corpuscles, particularly at the level of the glomerular basement laminae. These results as well as the known sensitivity of the mesonephros to thyroxine and the concordance between the steps of embryonic thyroid development and the mesonephric modifications show that the thyroid normally plays a major determining role in this phenomenon.

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