Open AccessMediastinal re‐staging of non small‐cell lung cancer
Author(s) -
Khoo KayLeong
Publication year - 2012
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/j.1759-7714.2011.00097.x
Subject(s) - medicine , mediastinum , lung cancer staging , radiology , mediastinal lymph node , lung cancer , endoscopic ultrasound , sampling (signal processing) , gold standard (test) , lymph node , cancer , mediastinoscopy , oncology , metastasis , pathology , filter (signal processing) , computer science , computer vision
Selected patients with non small‐cell lung cancer (NSCLC) with mediastinal lymph node involvement may have a survival benefit from surgical resection, particularly if mediastinal nodal down‐staging occurs after induction therapy and complete resection is achieved with lobectomy. Accurate re‐staging of the mediastinum after induction therapy is therefore crucial in determining prognosis and subsequent treatment. Non‐invasive imaging techniques usually require a confirmatory tissue sampling method to improve the accuracy of mediastinal re‐staging. As in the initial staging of the mediastinum, minimally invasive endosonography‐guided needle sampling techniques such as endobronchial ultrasound‐guided fine‐needle aspiration (EBUS‐TBNA) and endoscopic ultrasound‐guided fine‐needle aspiration show promise in re‐staging the mediastinum, though invasive surgical re‐staging remains the gold standard. Despite a lower sensitivity in the mediastinal re‐staging of NSCLC, EBUS‐TBNA with or without EUS‐FNA may still be the preferred initial mediastinal re‐staging technique.