Open AccessPrimary monophasic synovial sarcoma of the pleura: Neoadjuvant chemotherapy followed by complete resection
Author(s) -
Silva Ramiro G.M.,
Gross Jefferson L.,
Silva Rodrigo A.,
Haddad Fabio J.,
Younes Riad N.,
Cruz Vasco M.,
AvertanoRocha Antonio B.M.
Publication year - 2010
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/j.1759-7714.2010.00019.x
Subject(s) - medicine , synovial sarcoma , chemotherapy , extrapleural pneumonectomy , pathological , pneumonectomy , neoadjuvant therapy , sarcoma , surgery , radiology , lung , cancer , soft tissue , pathology , breast cancer
We describe a rare case of primary pleural synovial sarcoma in a 27‐year‐old man with a 4‐month history of dry cough and left‐sided chest pain. A CT scan showed a large cystic mass in the left pleural cavity. The patient underwent two video‐assisted thoracoscopic biopsies and the diagnosis of synovial sarcoma of the pleura was established. After neoadjuvant chemotherapy, which resulted in a partial response, the tumor was completely resected with extrapleural pneumonectomy. Pathological findings showed less than 5% of viable cancer and free surgical margins. The patient is clinically well 24 months after surgery, with no evidence of recurrent disease.