Premium
Thoracoscopic resection for a pulmonary nodule with the infiltrate of Ig G4 ‐positive plasma cells
Author(s) -
Odaka Makoto,
Mori Shohei,
Asano Hisatoshi,
Yamashita Makoto,
Kamiya Noriki,
Morikawa Toshiaki
Publication year - 2012
Publication title -
asian journal of endoscopic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.372
H-Index - 18
eISSN - 1758-5910
pISSN - 1758-5902
DOI - 10.1111/j.1758-5910.2012.00149.x
Subject(s) - medicine , lung cancer , histopathology , thoracotomy , immunostaining , lung , nodule (geology) , pathology , solitary pulmonary nodule , thoracoscopy , infiltration (hvac) , parenchyma , radiology , immunohistochemistry , surgery , paleontology , physics , biology , thermodynamics
This report describes a rare case of IgG4 ‐related lung disease that was difficult to distinguish from lung cancer. CT revealed a well‐demarcated round tumor in S10 of the right lung of a 56‐year‐old man suspected of having lung cancer. PET revealed high fluorodeoxyglucose uptake with a maximum standardized uptake value of 14.0. Because primary lung cancer was strongly suspected, lower lobectomy was performed via the thoracoscopic approach without mini‐thoracotomy. Histopathology showed lymphoplasmacytic infiltration. Immunostaining revealed numerous IgG4 ‐positive plasma cells diffusely infiltrating the tumor. Serum IgG4 levels increased, thereby confirming the diagnosis of IgG4 ‐related lung disease.