Premium
Short‐term results of laparoscopic surgery after preoperative chemoradiation for clinically staged T3 and T4 rectal cancer
Author(s) -
Hotchi Masanori,
Shimada Mitsuo,
Kurita Nobuhiro,
Iwata Takashi,
Sato Hirohiko,
Morimoto Shinya,
Yoshikawa Kozo,
Higashijima Jun,
Miyatani Tomohiko,
Mikami Chie,
Kashihara Hideya
Publication year - 2012
Publication title -
asian journal of endoscopic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.372
H-Index - 18
eISSN - 1758-5910
pISSN - 1758-5902
DOI - 10.1111/j.1758-5910.2012.00148.x
Subject(s) - medicine , perioperative , surgery , colorectal cancer , laparoscopic surgery , laparotomy , blood loss , lymph node , laparoscopy , open surgery , cancer
The feasibility of laparoscopic surgery for clinically staged T3 and T4 rectal cancer has not been clearly defined specifically in cases following preoperative chemoradiation therapy ( CRT ). Our aim was to investigate the feasibility of laparoscopic surgery after preoperative CRT for clinically staged T3 and T4 rectal cancer. Methods Between M ay 2003 and J une 2009, 57 patients ( T3 : n = 50, T4 : n = 7) who underwent preoperative CRT for rectal cancer were identified. Forty‐three patients with laparoscopic surgery ( L ap group) were compared with 14 patients who underwent open surgery ( O pen group). Perioperative data including postoperative morbidity were assessed between the two groups. Results All patients underwent complete laparoscopic operations, and none was converted to laparotomy. Operating time was longer in the O pen group (331 vs 375 min, P < 0.01). Blood loss was lower in the L ap group (160 vs 316 mL , P < 0.01). Lymph node harvest and morbidity rate were similar in both groups. The distal tumor margin was negative in all patients. No patients had perioperative mortality associated with surgery after CRT . Conclusion Laparoscopic surgery after preoperative CRT is a feasible and a safe option for T3 and T4 rectal cancer compared to conventional open surgery.