Premium
A case of Helicobacter pylori infection complicated with gastric cancer, gastric mucosa‐associated lymphoid tissue lymphoma, and idiopathic thrombocytopenic purpura successfully treated with laparoscopy‐assisted total gastrectomy and splenectomy
Author(s) -
Hamabe A,
Omori T,
Oyama T,
Akamatsu H,
Yoshidome K,
Tori M,
Ueshima S,
Tsujimoto M,
Nishida T
Publication year - 2011
Publication title -
asian journal of endoscopic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.372
H-Index - 18
eISSN - 1758-5910
pISSN - 1758-5902
DOI - 10.1111/j.1758-5910.2010.00067.x
Subject(s) - medicine , helicobacter pylori , thrombocytopenic purpura , gastroenterology , splenectomy , gastrectomy , cancer , gastric mucosa , gastric lymphoma , lymphoma , stomach , platelet , spleen
Helicobacter pylori infection plays a key role in the pathogenesis of H. pylori ‐associated diseases, including gastroduodenal and non‐gastroduodenal diseases. A 71‐year‐old man was evaluated for a positive fecal occult blood test by upper gastrointestinal endoscopy, which revealed H. pylori infection, two adenocarcinomas and two gastric mucosa‐associated lymphoid tissue lymphomas. Hematological examination revealed low platelet‐count, elevated platelet‐associated immunoglobulin G and anti‐ H. pylori immunoglobulin G antibodies. We diagnosed H. pylori infection complicated by simultaneous occurrence of gastric cancer, gastric mucosa‐associated lymphoid tissue lymphoma, and idiopathic thrombocytopenic purpura. These diseases were successfully treated with laparoscopy‐assisted total gastrectomy and splenectomy, and there was no evidence of recurrence for about 2 years. This is the first reported case of H. pylori infection complicated by these three diseases and cured with laparoscopic surgery.