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Vigor, Anxiety, and Depressive Symptoms as Predictors of Changes in Fibrinogen and C‐reactive Protein
Author(s) -
Shirom Arie,
Toker Sharon,
Melamed Samuel,
Berliner Shlomo,
Shapira Izhak
Publication year - 2010
Publication title -
applied psychology: health and well‐being
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.276
H-Index - 31
eISSN - 1758-0854
pISSN - 1758-0846
DOI - 10.1111/j.1758-0854.2010.01033.x
Subject(s) - fibrinogen , c reactive protein , anxiety , depressive symptoms , medicine , psychology , inflammation , psychiatry
We expected vigor to predict lower levels and depressive symptoms and anxiety to predict higher levels of high‐sensitivity C‐reactive protein (CRP) and fibrinogen across time. Participants ( N = 538 men and 203 women) were apparently healthy employees examined about three years apart (T1 and T2). We analysed our data separately for men and women, controlling for T1 level of the criterion. For the women, T1 vigor predicted lower T2 fibrinogen (controlling for T1 fibrinogen) and was curvilinearly associated with T2 CRP (controlling for T1 CRP). For the men, T1 vigor was curvilinearly associated with T2 fibrinogen and—for younger men only—T1 vigor predicted lower levels of T2 CRP, controlling for the T1 values of each criterion. T1 depressive symptoms and anxiety did not predict the T1 to T2 changes in fibrinogen and CRP. No support for possible reverse causation was found. We suggest that high levels of vigor may be implicated in reductions over time of CRP and fibrinogen concentrations among both men and women.