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Comparative cost‐effectiveness of three intrauterine devices: a multi‐center randomized trial
Author(s) -
Wen Jin,
Li Ying,
Li Youping,
Wang Li,
Zhou Jian,
Ba Lei,
Shen Suqi,
Wu Yulin
Publication year - 2010
Publication title -
journal of evidence‐based medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.885
H-Index - 22
ISSN - 1756-5391
DOI - 10.1111/j.1756-5391.2010.01075.x
Subject(s) - medicine , cost effectiveness , randomized controlled trial , gynecology , surgery , risk analysis (engineering)
Objective To determine the relative cost‐effectiveness of three intrauterine devices (IUDs), MLCu375, TCu380A, and YuangongCu365. Methods Cost‐effectiveness of three IUDs, namely MLCu375, TCu380A, and YuangongCu365, was analyzed from the provider's perspective by means of a randomized trial with one‐year follow‐up carried out in six centers in China. Results YuangongCu 365 had the lowest termination and pregnancy rates (4.17% and 0.54%, respectively), followed by TCu380A (8.59% and 1.11%, respectively) and MLCu375 (14.17% and 2.04%, respectively). YuangongCu365 was more effective yet more costly than the MLCu375. There was a favorably dominating trend of cost‐effectiveness for TCu380A comparing with MLCu375 when taking continuation rate as the effectiveness indicator, but there was no difference in cost‐effectiveness between the two IUDs when using the pregnancy avoidance rate as the effectiveness measure. Conclusions TCu380A is slightly more cost‐effective than the MLCu375. YuangongCu365 is the most effective of the three devices and be used provided it is economically affordable. The comparative long‐term safety and cost‐effectiveness of these devices need to be further investigated.